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human liver tumor derived cell lines snu387  (ATCC)


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    ATCC human liver tumor derived cell lines snu387
    FAM188B expression is upregulated and associated with poor prognosis in hepatocellular carcinoma (HCC). (A) Expression of FAM188B mRNA in tumor and non-tumor tissues and its association with cancer stage and tumor grade in UALCAN database. (B) The expression of FAM188B protein was evaluated in normal hepatocytes (LX-2) and in hepatocellular carcinoma (HCC) cells (MHCC97H, Huh7, Hep3B and <t>SNU387)</t> by western blot. (C) Validation of FAM188B expression after overexpression in the indicated cell lines using western blotting (n = 3). (D) Proliferation of MHCC97H and Huh7 cells, as detected by performing CCK-8 assays (n = 10). (E) Migratory and invasive capacities of MHCC97H and Huh7 cells within 24 hours, as evaluated using Transwell assays (scale bar, 50 μm) (n = 3). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, ns, not significant. The data are expressed as the mean ± SD of three independent experiments.
    Human Liver Tumor Derived Cell Lines Snu387, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 293 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+liver+tumor+derived+cell+lines+snu387/SNU-387/pmc13003555-38-0-17
    Average 96 stars, based on 293 article reviews
    human liver tumor derived cell lines snu387 - by Bioz Stars, 2026-09
    96/100 stars

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    1) Product Images from "FAM188B promotes progression of hepatocellular carcinoma by regulating YAP/TAZ via interaction with USP10"

    Article Title: FAM188B promotes progression of hepatocellular carcinoma by regulating YAP/TAZ via interaction with USP10

    Journal: Journal of Cancer

    doi: 10.7150/jca.125659

    FAM188B expression is upregulated and associated with poor prognosis in hepatocellular carcinoma (HCC). (A) Expression of FAM188B mRNA in tumor and non-tumor tissues and its association with cancer stage and tumor grade in UALCAN database. (B) The expression of FAM188B protein was evaluated in normal hepatocytes (LX-2) and in hepatocellular carcinoma (HCC) cells (MHCC97H, Huh7, Hep3B and SNU387) by western blot. (C) Validation of FAM188B expression after overexpression in the indicated cell lines using western blotting (n = 3). (D) Proliferation of MHCC97H and Huh7 cells, as detected by performing CCK-8 assays (n = 10). (E) Migratory and invasive capacities of MHCC97H and Huh7 cells within 24 hours, as evaluated using Transwell assays (scale bar, 50 μm) (n = 3). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, ns, not significant. The data are expressed as the mean ± SD of three independent experiments.
    Figure Legend Snippet: FAM188B expression is upregulated and associated with poor prognosis in hepatocellular carcinoma (HCC). (A) Expression of FAM188B mRNA in tumor and non-tumor tissues and its association with cancer stage and tumor grade in UALCAN database. (B) The expression of FAM188B protein was evaluated in normal hepatocytes (LX-2) and in hepatocellular carcinoma (HCC) cells (MHCC97H, Huh7, Hep3B and SNU387) by western blot. (C) Validation of FAM188B expression after overexpression in the indicated cell lines using western blotting (n = 3). (D) Proliferation of MHCC97H and Huh7 cells, as detected by performing CCK-8 assays (n = 10). (E) Migratory and invasive capacities of MHCC97H and Huh7 cells within 24 hours, as evaluated using Transwell assays (scale bar, 50 μm) (n = 3). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, ns, not significant. The data are expressed as the mean ± SD of three independent experiments.

    Techniques Used: Expressing, Western Blot, Biomarker Discovery, Over Expression, CCK-8 Assay

    FAM188B interacts with USP10. (A) Schematic illustration of IP and GO enrichment of identified proteins (using all proteins in the species database as the background). Fisher's exact test was used to analyze the significance and P value < 0.05 were considered significant. (B) Expression levels of USP10 mRNA in tumor (n = 374) and non-tumor (n = 50) tissues and its relationship with FAM188B, based on a public database. (C) The protein expression level of USP10 was evaluated in normal hepatocytes (LX-2) and hepatocellular carcinoma (HCC) cells (MHCC97H, Huh7, Hep3B and SNU387) by western blot. (D) Localization of USP10 in HCC cells (scale bar, 20 μm). (E) Co-IP assays to confirm the protein-protein interaction between FAM188B and USP10 in vitro . **p < 0.01, ***p < 0.001. The data are expressed as the mean ± SD of three independent experiments. IP, immunoprecipitation. Co-IP, co-immunoprecipitation.
    Figure Legend Snippet: FAM188B interacts with USP10. (A) Schematic illustration of IP and GO enrichment of identified proteins (using all proteins in the species database as the background). Fisher's exact test was used to analyze the significance and P value < 0.05 were considered significant. (B) Expression levels of USP10 mRNA in tumor (n = 374) and non-tumor (n = 50) tissues and its relationship with FAM188B, based on a public database. (C) The protein expression level of USP10 was evaluated in normal hepatocytes (LX-2) and hepatocellular carcinoma (HCC) cells (MHCC97H, Huh7, Hep3B and SNU387) by western blot. (D) Localization of USP10 in HCC cells (scale bar, 20 μm). (E) Co-IP assays to confirm the protein-protein interaction between FAM188B and USP10 in vitro . **p < 0.01, ***p < 0.001. The data are expressed as the mean ± SD of three independent experiments. IP, immunoprecipitation. Co-IP, co-immunoprecipitation.

    Techniques Used: Expressing, Western Blot, Co-Immunoprecipitation Assay, In Vitro, Immunoprecipitation

    Related Articles

    Expressing:

    Article Title: FAM188B promotes progression of hepatocellular carcinoma by regulating YAP/TAZ via interaction with USP10
    Article Snippet: The normal human liver cell line LX-2 was obtained in 2025, while the human liver tumor-derived cell lines MHCC97H and Huh7 were obtained from Whelab Biotechnology LTD (Shanghai, China) in 2021.The normal human liver cell line LX-2 was obtained in 2025, while the human liver tumor-derived cell lines MHCC97H and Huh7 were obtained from Whelab Biotechnology LTD (Shanghai, China) in 2021.. Human liver tumor-derived cell lines SNU387 and Hep3B, human embryonic kidney HEK293T cells were obtained from the American Type Culture Collection (Manassas, VA, USA) in 2021.. All cell lines were maintained in DMEM, MEM or RPMI-1640 media (Gibco, Grand Island, NY, USA) supplemented with 10% foetal bovine serum (FBS; Sigma- Aldrich, St. Louis, MO, USA) at 37°C, in a 5% CO2 humid atmosphere.All cell lines were maintained in DMEM, MEM or RPMI-1640 media (Gibco, Grand Island, NY, USA) supplemented with 10% foetal bovine serum (FBS; Sigma- Aldrich, St. Louis, MO, USA) at 37°C, in a 5% CO2 humid atmosphere.

    Western Blot:

    Article Title: FAM188B promotes progression of hepatocellular carcinoma by regulating YAP/TAZ via interaction with USP10
    Article Snippet: The normal human liver cell line LX-2 was obtained in 2025, while the human liver tumor-derived cell lines MHCC97H and Huh7 were obtained from Whelab Biotechnology LTD (Shanghai, China) in 2021.The normal human liver cell line LX-2 was obtained in 2025, while the human liver tumor-derived cell lines MHCC97H and Huh7 were obtained from Whelab Biotechnology LTD (Shanghai, China) in 2021.. Human liver tumor-derived cell lines SNU387 and Hep3B, human embryonic kidney HEK293T cells were obtained from the American Type Culture Collection (Manassas, VA, USA) in 2021.. All cell lines were maintained in DMEM, MEM or RPMI-1640 media (Gibco, Grand Island, NY, USA) supplemented with 10% foetal bovine serum (FBS; Sigma- Aldrich, St. Louis, MO, USA) at 37°C, in a 5% CO2 humid atmosphere.All cell lines were maintained in DMEM, MEM or RPMI-1640 media (Gibco, Grand Island, NY, USA) supplemented with 10% foetal bovine serum (FBS; Sigma- Aldrich, St. Louis, MO, USA) at 37°C, in a 5% CO2 humid atmosphere.

    Biomarker Discovery:

    Article Title: FAM188B promotes progression of hepatocellular carcinoma by regulating YAP/TAZ via interaction with USP10
    Article Snippet: The normal human liver cell line LX-2 was obtained in 2025, while the human liver tumor-derived cell lines MHCC97H and Huh7 were obtained from Whelab Biotechnology LTD (Shanghai, China) in 2021.The normal human liver cell line LX-2 was obtained in 2025, while the human liver tumor-derived cell lines MHCC97H and Huh7 were obtained from Whelab Biotechnology LTD (Shanghai, China) in 2021.. Human liver tumor-derived cell lines SNU387 and Hep3B, human embryonic kidney HEK293T cells were obtained from the American Type Culture Collection (Manassas, VA, USA) in 2021.. All cell lines were maintained in DMEM, MEM or RPMI-1640 media (Gibco, Grand Island, NY, USA) supplemented with 10% foetal bovine serum (FBS; Sigma- Aldrich, St. Louis, MO, USA) at 37°C, in a 5% CO2 humid atmosphere.All cell lines were maintained in DMEM, MEM or RPMI-1640 media (Gibco, Grand Island, NY, USA) supplemented with 10% foetal bovine serum (FBS; Sigma- Aldrich, St. Louis, MO, USA) at 37°C, in a 5% CO2 humid atmosphere.

    Over Expression:

    Article Title: FAM188B promotes progression of hepatocellular carcinoma by regulating YAP/TAZ via interaction with USP10
    Article Snippet: The normal human liver cell line LX-2 was obtained in 2025, while the human liver tumor-derived cell lines MHCC97H and Huh7 were obtained from Whelab Biotechnology LTD (Shanghai, China) in 2021.The normal human liver cell line LX-2 was obtained in 2025, while the human liver tumor-derived cell lines MHCC97H and Huh7 were obtained from Whelab Biotechnology LTD (Shanghai, China) in 2021.. Human liver tumor-derived cell lines SNU387 and Hep3B, human embryonic kidney HEK293T cells were obtained from the American Type Culture Collection (Manassas, VA, USA) in 2021.. All cell lines were maintained in DMEM, MEM or RPMI-1640 media (Gibco, Grand Island, NY, USA) supplemented with 10% foetal bovine serum (FBS; Sigma- Aldrich, St. Louis, MO, USA) at 37°C, in a 5% CO2 humid atmosphere.All cell lines were maintained in DMEM, MEM or RPMI-1640 media (Gibco, Grand Island, NY, USA) supplemented with 10% foetal bovine serum (FBS; Sigma- Aldrich, St. Louis, MO, USA) at 37°C, in a 5% CO2 humid atmosphere.

    CCK-8 Assay:

    Article Title: FAM188B promotes progression of hepatocellular carcinoma by regulating YAP/TAZ via interaction with USP10
    Article Snippet: The normal human liver cell line LX-2 was obtained in 2025, while the human liver tumor-derived cell lines MHCC97H and Huh7 were obtained from Whelab Biotechnology LTD (Shanghai, China) in 2021.The normal human liver cell line LX-2 was obtained in 2025, while the human liver tumor-derived cell lines MHCC97H and Huh7 were obtained from Whelab Biotechnology LTD (Shanghai, China) in 2021.. Human liver tumor-derived cell lines SNU387 and Hep3B, human embryonic kidney HEK293T cells were obtained from the American Type Culture Collection (Manassas, VA, USA) in 2021.. All cell lines were maintained in DMEM, MEM or RPMI-1640 media (Gibco, Grand Island, NY, USA) supplemented with 10% foetal bovine serum (FBS; Sigma- Aldrich, St. Louis, MO, USA) at 37°C, in a 5% CO2 humid atmosphere.All cell lines were maintained in DMEM, MEM or RPMI-1640 media (Gibco, Grand Island, NY, USA) supplemented with 10% foetal bovine serum (FBS; Sigma- Aldrich, St. Louis, MO, USA) at 37°C, in a 5% CO2 humid atmosphere.

    Co-Immunoprecipitation Assay:

    Article Title: FAM188B promotes progression of hepatocellular carcinoma by regulating YAP/TAZ via interaction with USP10
    Article Snippet: The normal human liver cell line LX-2 was obtained in 2025, while the human liver tumor-derived cell lines MHCC97H and Huh7 were obtained from Whelab Biotechnology LTD (Shanghai, China) in 2021.The normal human liver cell line LX-2 was obtained in 2025, while the human liver tumor-derived cell lines MHCC97H and Huh7 were obtained from Whelab Biotechnology LTD (Shanghai, China) in 2021.. Human liver tumor-derived cell lines SNU387 and Hep3B, human embryonic kidney HEK293T cells were obtained from the American Type Culture Collection (Manassas, VA, USA) in 2021.. All cell lines were maintained in DMEM, MEM or RPMI-1640 media (Gibco, Grand Island, NY, USA) supplemented with 10% foetal bovine serum (FBS; Sigma- Aldrich, St. Louis, MO, USA) at 37°C, in a 5% CO2 humid atmosphere.All cell lines were maintained in DMEM, MEM or RPMI-1640 media (Gibco, Grand Island, NY, USA) supplemented with 10% foetal bovine serum (FBS; Sigma- Aldrich, St. Louis, MO, USA) at 37°C, in a 5% CO2 humid atmosphere.

    In Vitro:

    Article Title: FAM188B promotes progression of hepatocellular carcinoma by regulating YAP/TAZ via interaction with USP10
    Article Snippet: The normal human liver cell line LX-2 was obtained in 2025, while the human liver tumor-derived cell lines MHCC97H and Huh7 were obtained from Whelab Biotechnology LTD (Shanghai, China) in 2021.The normal human liver cell line LX-2 was obtained in 2025, while the human liver tumor-derived cell lines MHCC97H and Huh7 were obtained from Whelab Biotechnology LTD (Shanghai, China) in 2021.. Human liver tumor-derived cell lines SNU387 and Hep3B, human embryonic kidney HEK293T cells were obtained from the American Type Culture Collection (Manassas, VA, USA) in 2021.. All cell lines were maintained in DMEM, MEM or RPMI-1640 media (Gibco, Grand Island, NY, USA) supplemented with 10% foetal bovine serum (FBS; Sigma- Aldrich, St. Louis, MO, USA) at 37°C, in a 5% CO2 humid atmosphere.All cell lines were maintained in DMEM, MEM or RPMI-1640 media (Gibco, Grand Island, NY, USA) supplemented with 10% foetal bovine serum (FBS; Sigma- Aldrich, St. Louis, MO, USA) at 37°C, in a 5% CO2 humid atmosphere.

    Immunoprecipitation:

    Article Title: FAM188B promotes progression of hepatocellular carcinoma by regulating YAP/TAZ via interaction with USP10
    Article Snippet: The normal human liver cell line LX-2 was obtained in 2025, while the human liver tumor-derived cell lines MHCC97H and Huh7 were obtained from Whelab Biotechnology LTD (Shanghai, China) in 2021.The normal human liver cell line LX-2 was obtained in 2025, while the human liver tumor-derived cell lines MHCC97H and Huh7 were obtained from Whelab Biotechnology LTD (Shanghai, China) in 2021.. Human liver tumor-derived cell lines SNU387 and Hep3B, human embryonic kidney HEK293T cells were obtained from the American Type Culture Collection (Manassas, VA, USA) in 2021.. All cell lines were maintained in DMEM, MEM or RPMI-1640 media (Gibco, Grand Island, NY, USA) supplemented with 10% foetal bovine serum (FBS; Sigma- Aldrich, St. Louis, MO, USA) at 37°C, in a 5% CO2 humid atmosphere.All cell lines were maintained in DMEM, MEM or RPMI-1640 media (Gibco, Grand Island, NY, USA) supplemented with 10% foetal bovine serum (FBS; Sigma- Aldrich, St. Louis, MO, USA) at 37°C, in a 5% CO2 humid atmosphere.



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    human liver tumor derived cell lines snu387  (ATCC)
    96
    ATCC human liver tumor derived cell lines snu387
    FAM188B expression is upregulated and associated with poor prognosis in hepatocellular carcinoma (HCC). (A) Expression of FAM188B mRNA in tumor and non-tumor tissues and its association with cancer stage and tumor grade in UALCAN database. (B) The expression of FAM188B protein was evaluated in normal hepatocytes (LX-2) and in hepatocellular carcinoma (HCC) cells (MHCC97H, Huh7, Hep3B and <t>SNU387)</t> by western blot. (C) Validation of FAM188B expression after overexpression in the indicated cell lines using western blotting (n = 3). (D) Proliferation of MHCC97H and Huh7 cells, as detected by performing CCK-8 assays (n = 10). (E) Migratory and invasive capacities of MHCC97H and Huh7 cells within 24 hours, as evaluated using Transwell assays (scale bar, 50 μm) (n = 3). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, ns, not significant. The data are expressed as the mean ± SD of three independent experiments.
    Human Liver Tumor Derived Cell Lines Snu387, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+liver+tumor+derived+cell+lines+snu387/SNU-387/pmc13003555-38-0-17
    Average 96 stars, based on 1 article reviews
    human liver tumor derived cell lines snu387 - by Bioz Stars, 2026-09
    96/100 stars
    		  Buy from Supplier

    Image Search Results


    FAM188B expression is upregulated and associated with poor prognosis in hepatocellular carcinoma (HCC). (A) Expression of FAM188B mRNA in tumor and non-tumor tissues and its association with cancer stage and tumor grade in UALCAN database. (B) The expression of FAM188B protein was evaluated in normal hepatocytes (LX-2) and in hepatocellular carcinoma (HCC) cells (MHCC97H, Huh7, Hep3B and SNU387) by western blot. (C) Validation of FAM188B expression after overexpression in the indicated cell lines using western blotting (n = 3). (D) Proliferation of MHCC97H and Huh7 cells, as detected by performing CCK-8 assays (n = 10). (E) Migratory and invasive capacities of MHCC97H and Huh7 cells within 24 hours, as evaluated using Transwell assays (scale bar, 50 μm) (n = 3). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, ns, not significant. The data are expressed as the mean ± SD of three independent experiments.

    Journal: Journal of Cancer

    Article Title: FAM188B promotes progression of hepatocellular carcinoma by regulating YAP/TAZ via interaction with USP10

    doi: 10.7150/jca.125659

    Figure Lengend Snippet: FAM188B expression is upregulated and associated with poor prognosis in hepatocellular carcinoma (HCC). (A) Expression of FAM188B mRNA in tumor and non-tumor tissues and its association with cancer stage and tumor grade in UALCAN database. (B) The expression of FAM188B protein was evaluated in normal hepatocytes (LX-2) and in hepatocellular carcinoma (HCC) cells (MHCC97H, Huh7, Hep3B and SNU387) by western blot. (C) Validation of FAM188B expression after overexpression in the indicated cell lines using western blotting (n = 3). (D) Proliferation of MHCC97H and Huh7 cells, as detected by performing CCK-8 assays (n = 10). (E) Migratory and invasive capacities of MHCC97H and Huh7 cells within 24 hours, as evaluated using Transwell assays (scale bar, 50 μm) (n = 3). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, ns, not significant. The data are expressed as the mean ± SD of three independent experiments.

    Article Snippet: Human liver tumor-derived cell lines SNU387 and Hep3B, human embryonic kidney HEK293T cells were obtained from the American Type Culture Collection (Manassas, VA, USA) in 2021.

    Techniques: Expressing, Western Blot, Biomarker Discovery, Over Expression, CCK-8 Assay

    FAM188B interacts with USP10. (A) Schematic illustration of IP and GO enrichment of identified proteins (using all proteins in the species database as the background). Fisher's exact test was used to analyze the significance and P value < 0.05 were considered significant. (B) Expression levels of USP10 mRNA in tumor (n = 374) and non-tumor (n = 50) tissues and its relationship with FAM188B, based on a public database. (C) The protein expression level of USP10 was evaluated in normal hepatocytes (LX-2) and hepatocellular carcinoma (HCC) cells (MHCC97H, Huh7, Hep3B and SNU387) by western blot. (D) Localization of USP10 in HCC cells (scale bar, 20 μm). (E) Co-IP assays to confirm the protein-protein interaction between FAM188B and USP10 in vitro . **p < 0.01, ***p < 0.001. The data are expressed as the mean ± SD of three independent experiments. IP, immunoprecipitation. Co-IP, co-immunoprecipitation.

    Journal: Journal of Cancer

    Article Title: FAM188B promotes progression of hepatocellular carcinoma by regulating YAP/TAZ via interaction with USP10

    doi: 10.7150/jca.125659

    Figure Lengend Snippet: FAM188B interacts with USP10. (A) Schematic illustration of IP and GO enrichment of identified proteins (using all proteins in the species database as the background). Fisher's exact test was used to analyze the significance and P value < 0.05 were considered significant. (B) Expression levels of USP10 mRNA in tumor (n = 374) and non-tumor (n = 50) tissues and its relationship with FAM188B, based on a public database. (C) The protein expression level of USP10 was evaluated in normal hepatocytes (LX-2) and hepatocellular carcinoma (HCC) cells (MHCC97H, Huh7, Hep3B and SNU387) by western blot. (D) Localization of USP10 in HCC cells (scale bar, 20 μm). (E) Co-IP assays to confirm the protein-protein interaction between FAM188B and USP10 in vitro . **p < 0.01, ***p < 0.001. The data are expressed as the mean ± SD of three independent experiments. IP, immunoprecipitation. Co-IP, co-immunoprecipitation.

    Article Snippet: Human liver tumor-derived cell lines SNU387 and Hep3B, human embryonic kidney HEK293T cells were obtained from the American Type Culture Collection (Manassas, VA, USA) in 2021.

    Techniques: Expressing, Western Blot, Co-Immunoprecipitation Assay, In Vitro, Immunoprecipitation